Molecular adaptation of Borrelia burgdorferi in the murine host

An analysis of expression of 137 lipoprotein genes on the course of murine infection revealed a two-step molecular adaptation by Borrelia burgdorferi, the Lyme disease spirochete. For the first step, regardless whether the initial inocula of B. burgdorferi expressed either all (cultured spirochetes)...

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Veröffentlicht in:	The Journal of experimental medicine 2002-07, Vol.196 (2), p.275-280
Hauptverfasser:	Liang, Fang Ting, Nelson, F Kenneth, Fikrig, Erol
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptation, Physiological Animals Antibodies, Bacterial - biosynthesis Arachnid Vectors - microbiology Bacterial Proteins - genetics Borrelia burgdorferi - genetics Borrelia burgdorferi - growth & development Borrelia burgdorferi - immunology Borrelia burgdorferi - physiology Brief Definitive Report Gene Expression Profiling Genes, Bacterial Lipoproteins - genetics Lyme Disease - immunology Lyme Disease - microbiology Mice Mice, Inbred C3H Mice, SCID Oligonucleotide Array Sequence Analysis Ticks - microbiology
Online-Zugang:	Volltext
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