Interferon γ receptor deficient mice are resistant to endotoxic shock

Antibody neutralization studies have established interferon gamma (IFN-gamma) as a critical mediator of endotoxic shock. The advent of IFN-gamma receptor negative (IFN gamma R-/-) mutant mice has enabled a more direct assessment of the role of IFN-gamma in endotoxin (lipopolysaccharide [LPS]-induced...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The Journal of experimental medicine 1994-05, Vol.179 (5), p.1437-1444
Hauptverfasser:	CAR, B. D, ENG, V. M, SCHNYDER, B, OZMEN, L, SUI HUANG, GALLAY, P, HEUMANN, D, AGUET, M, RYFFEL, B
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bacterial diseases Biological and medical sciences Body Weight Endotoxins Experimental bacterial diseases and models Immunity, Innate Infectious diseases Interferon gamma Receptor Lipopolysaccharides - toxicity Medical sciences Mice Molecular Sequence Data Receptors, Interferon - deficiency Receptors, Interferon - immunology Shock, Septic - immunology Tumor Necrosis Factor-alpha - analysis
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!