Tumor necrosis factor and stroke: role of the blood-brain barrier

The progression and outcome of stroke is affected by the intricate relationship between the blood-brain barrier (BBB) and tumor necrosis factor alpha (TNFalpha). TNFalpha crosses the intact BBB by a receptor-mediated transport system that is upregulated by CNS trauma and inflammation. In this review...

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Veröffentlicht in:	Progress in neurobiology 2007-12, Vol.83 (6), p.363-374
Hauptverfasser:	Pan, Weihong, Kastin, Abba J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Blood-Brain Barrier - physiopathology Humans Protein Transport - physiology Stroke - metabolism Stroke - physiopathology Tumor Necrosis Factor-alpha - metabolism
Online-Zugang:	Volltext
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