Endothelial receptor-mediated binding of glucose-modified albumin is associated with increased monolayer permeability and modulation of cell surface coagulant properties

Advanced glycosylation end products (AGE) of proteins accumulate in the vasculature with diabetes and aging, and are thought to be associated with vascular complications. This led us to examine the interaction of AGE-BSA as a prototype of this class of nonenzymatically glycosylated proteins subjecte...

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Veröffentlicht in:The Journal of experimental medicine 1989-10, Vol.170 (4), p.1387-1407
Hauptverfasser: Esposito, C, Gerlach, H, Brett, J, Stern, D, Vlassara, H
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Sprache:eng
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