Primary stimulation by dendritic cells induces antiviral proliferative and cytotoxic T cell responses in vitro

We used well-gassed hanging drop (20 microliters) cultures with high concentrations of purified T cells from normal BALB/c mice to examine whether dendritic cells (DC) can induce primary antiviral proliferative T cell responses and generate virus-specific CTL. We found that DC exposed to infectious...

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Veröffentlicht in:	The Journal of experimental medicine 1989-04, Vol.169 (4), p.1255-1264
Hauptverfasser:	MACATONIA, S. E, TAYLOR, P. M, KNIGHT, S. C, ASKONAS, B. A
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis of the immune response. Humoral and cellular immunity Animals Antigens, Viral - immunology Biological and medical sciences Cell interactions Cells, Cultured Dendritic Cells - immunology Dose-Response Relationship, Immunologic Fundamental and applied biological sciences. Psychology Fundamental immunology Immunobiology In Vitro Techniques Influenza A virus - immunology influenza virus Lymphocyte Activation Mice T-Lymphocytes, Cytotoxic - immunology
Online-Zugang:	Volltext
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