Regulation of autoimmunity and donor cell engraftment by recipient Lyt-2+ cells during the graft-versus-host reaction

When lymphocytes from DBA/2 mice are transferred to (C57BL X DBA/2)F1 (BDF1) mice, the ensuing graft-vs.-host reaction (GVHR) causes an autoimmune illness resembling human SLE. To examine the role of recipient T cells in this process, BDF1 mice were depleted of L3T4+ or Lyt-2+ cells by thymectomy fo...

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Veröffentlicht in:	The Journal of experimental medicine 1987-09, Vol.166 (3), p.657-667
Hauptverfasser:	HARPER, S. E, ROUBINIAN, J. R, SEAMAN, W. E
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Applied sciences Autoantibodies - immunology Autoimmune Diseases - immunology Exact sciences and technology Female Graft vs Host Reaction Mice Mice, Inbred C57BL Mice, Inbred DBA Other techniques and industries T-Lymphocytes - transplantation T-Lymphocytes, Cytotoxic - immunology T-Lymphocytes, Helper-Inducer - immunology T-Lymphocytes, Regulatory - immunology Thymectomy
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