Sera from patients with poststreptococcal glomerulonephritis contain antibodies to glomerular heparan sulfate proteoglycan

Antibodies, found in human sera from patients with poststreptococcal glomerulonephritis, against proteoglycans (PG) derived from bovine and human glomeruli were investigated. PG were isolated by 4 M guanidine-HCl extraction of whole glomeruli, followed by DEAE-Sepharose CL-6B ion exchange chromatogr...

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Veröffentlicht in:	The Journal of experimental medicine 1985-02, Vol.161 (2), p.277-289
Hauptverfasser:	FILLIT, H, DAMLE, S. P, GREGORY, J. D, VOLIN, C, POON-KING, T, ZABRISKIE, J
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease Animals Antigen-Antibody Reactions Autoantibodies - analysis Biological and medical sciences Cattle Chemical Phenomena Chemistry, Physical Chondroitin Sulfate Proteoglycans - analysis Chondroitin Sulfate Proteoglycans - immunology Chondroitin Sulfate Proteoglycans - isolation & purification Enzyme-Linked Immunosorbent Assay Glomerulonephritis Glomerulonephritis - etiology Glomerulonephritis - immunology Glycosaminoglycans - immunology Heparan Sulfate Proteoglycans Heparitin Sulfate - analysis Heparitin Sulfate - immunology Heparitin Sulfate - isolation & purification Hexosamines - isolation & purification Humans Kidney Glomerulus - immunology Medical sciences Nephrology. Urinary tract diseases Nephropathies. Renovascular diseases. Renal failure Proteins - isolation & purification Proteoglycans - immunology Rabbits Streptococcal Infections - immunology Uronic Acids - isolation & purification
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