Human monoclonal anti-keyhole limpet hemocyanin antibody-secreting hybridoma produced from peripheral blood B lymphocytes of a keyhole limpet hemocyanin-immune individual

A human IgMk monoclonal antibody, 2F7, of predetermined specificity, has been produced by the fusion of human peripheral blood lymphocytes with the nonsecreting mouse myeloma line SP-1. The heterohybridoma has remained stable for over 8 mo, with culture supernatants containing up to 30 micrograms/ml...

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Veröffentlicht in:	The Journal of experimental medicine 1982-01, Vol.155 (1), p.333-338
Hauptverfasser:	Lane, H C, Shelhamer, J H, Mostowski, H S, Fauci, A S
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Monoclonal - biosynthesis Antibodies, Monoclonal - immunology Antibody-Producing Cells - immunology B-Lymphocytes - immunology Hemocyanins - immunology Humans Hybridomas - immunology Hybridomas - metabolism Mice Mice, Inbred BALB C
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