The expression of anti-poly(LGlu60, LPhe40) idiotypic determinants dictated by the gene products in the major histocompatibility complex

Antibodies raised in SWR/J mice (H-2q, Igc) to the random copolymer poly(LGlu60, LPhe40) (GPhe) were purified by immunoadsorbent chromatography and used to immunize a New Zealand red rabbit. The rabbit anti-idiotypic antiserum thus produced strongly inhibited the binding of 125I-GPhe by anti-GPhe an...

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Veröffentlicht in:	The Journal of experimental medicine 1981-09, Vol.154 (3), p.649-658
Hauptverfasser:	Babu, U M, Maurer, P H
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Anti-Idiotypic Antigen-Antibody Reactions Genes, MHC Class II Glutamates Glutamic Acid H-2 Antigens - genetics Immunoglobulin Allotypes Immunoglobulin Idiotypes - genetics Major Histocompatibility Complex Mice Peptides - immunology Phenylalanine
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