Bone marrow origin of Ia-positive cells in the medulla rat thymus

Irradiated rats were reconstituted with bone marrow from F1 hybrids. Ia antigen of donor-bone marrow origin was detected by an immunoperoxidase technique on cryostat sections and found predominantly in the medulla of rat thymus 2 wk after reconstitution. These Ia-bearing cells increased in number wi...

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Veröffentlicht in:	J. Exp. Med.; (United States) 1981-06, Vol.153 (6), p.1666-1671
Hauptverfasser:	Barclay, A N, Mayrhofer, G
Format:	Artikel
Sprache:	eng
Schlagworte:	560300 - Chemicals Metabolism & Toxicology ANIMAL CELLS ANIMAL TISSUES ANIMALS ANTIGENS BODY BONE MARROW Bone Marrow - immunology BONE MARROW CELLS CARBOXYLIC ACIDS CELL DIFFERENTIATION CHIMERAS CONNECTIVE TISSUE CELLS ENZYMES HEMATOPOIETIC SYSTEM HETEROCYCLIC ACIDS HETEROCYCLIC COMPOUNDS Histocompatibility Antigens Class II - analysis IMMUNOLOGY LYMPHATIC SYSTEM Major Histocompatibility Complex MAMMALS Mice MOSAICISM ORGANIC ACIDS ORGANIC COMPOUNDS ORGANIC NITROGEN COMPOUNDS ORGANS OXIDOREDUCTASES PEROXIDASES PORPHYRINS Radiation Chimera RADIATION CHIMERAS RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT RATS RODENTS SOMATIC CELLS THYMUS Thymus Gland - cytology Thymus Gland - immunology TISSUES VERTEBRATES
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