T lymphocyte-mediated suppression of myeloma function in vitro. II. Evidence for regulation of hapten-binding myelomas by syngeneic hapten-specific cytolytic T lymphocytes

BALB/c splenocytes stimulated in vitro with trinitrophenyl (TNP)-modified syngeneic cells inhibit the secretion of antibody by the TNP-binding BALB/c myeloma MOPC 315 in the presence of soluble TNP-Keyhole limpet hemocyanin (KLH). The effector cells are hapten-specific, H-2-restricted, Thy-1.2-beari...

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Veröffentlicht in:	The Journal of experimental medicine 1980-08, Vol.152 (2), p.306-323
Hauptverfasser:	Abbas, A K, Ratnofsky, S E, Burakoff, S J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Line Cytotoxicity, Immunologic Epitopes H-2 Antigens - immunology Haptens - immunology Haptens - metabolism Immunosuppression Multiple Myeloma - immunology Multiple Myeloma - metabolism Receptors, Antigen - metabolism T-Lymphocytes - immunology Trinitrobenzenes - pharmacology
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