Cytokeratins 8 and 19 in the Mouse Placental Development

To investigate the expression and biological roles of cytokeratin 19 (K19) in development and in adult tissues, we inactivated the mouse K19 gene (Krt1-19) by inserting a bacterial β-galactosidase gene (lacZ) by homologous recombination in embryonic stem cells, and established germ line mutant mice....

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The Journal of cell biology 2000-10, Vol.151 (3), p.563-572
Hauptverfasser:	Tamai, Yoshitaka, Tomo-o Ishikawa, Bösl, Michael R., Mori, Masahiko, Nozaki, Masami, Baribault, Heléne, Oshima, Robert G., Taketo, Makoto M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles Animals Cells Crosses, Genetic Embryo, Mammalian - blood supply Embryo, Mammalian - embryology Embryo, Mammalian - metabolism Embryos Female Fetal Death Fetal Growth Retardation Fluorescent Antibody Technique Galactosidases - genetics Galactosidases - metabolism Gene Deletion Gene Targeting Genes Genes, Reporter Genotype Germ-Line Mutation - genetics Giant cells Homozygotes In Situ Hybridization Keratins Keratins - genetics Keratins - metabolism Male Mice Mice, Inbred C57BL Mice, Inbred Strains Mice, Knockout Original Phenotype Placenta Placenta - blood supply Placenta - embryology Placenta - metabolism Placenta - pathology Placental Circulation Pregnancy Recombination, Genetic RNA, Messenger - analysis RNA, Messenger - genetics Rodents Stem cells Stem Cells - metabolism Trophoblasts Trophoblasts - metabolism Trophoblasts - pathology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!