Maintenance of hemopoietic stem cells and production of differentiated progeny in allogeneic and semiallogeneic bone marrow chimeras in vitro

A culture system is described in which bone marrow-derived adherent cells can support prolonged proliferation and differentiation of genetically incompatible stem cells and precursor cells. The results suggest that the reactive cells responsible in vivo for host transplantation resistance and for gr...

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Veröffentlicht in:	The Journal of experimental medicine 1977-06, Vol.145 (6), p.1612-1616
Hauptverfasser:	Dexter, T M, Moore, M A, Sheridan, A P
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bone Marrow Cells Bone Marrow Transplantation Cell Differentiation Cell Division Cells, Cultured Chimera Hematopoietic Stem Cells - physiology Isoantigens Mice Mice, Inbred C57BL Mice, Inbred CBA Mosaicism Transplantation, Heterologous
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