PRODUCTION OF A RUNTING SYNDROME AND SELECTIVE γA DEFICIENCY IN MICE BY THE ADMINISTRATION OF ANTI-HEAVY CHAIN ANTISERA

Conventional Swiss mice were treated from birth with intraperitoneal injections of anti-immunoglobulins in an attempt to create an experimental dysgammaglobulinemia. Mice treated with anti-γM were immunologically suppressed in all immunoglobulin classes as determined by serum antibody titers, spleni...

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Veröffentlicht in:The Journal of experimental medicine 1973-07, Vol.138 (1), p.209-228
Hauptverfasser: Murgita, Robert A., Mattioli, Carlos A., Tomasi, Thomas B.
Format: Artikel
Sprache:eng
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