Histone MacroH2A1.2 Relocates to the Inactive X Chromosome after Initiation and Propagation of X-Inactivation

The histone macroH2A1.2 has been implicated in X chromosome inactivation on the basis of its accumulation on the inactive X chromosome (Xi) of adult female mammals. We have established the timing of macroH2A1.2 association with the Xi relative to the onset of X-inactivation in differentiating murine...

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