Nectin: An Adhesion Molecule Involved in Formation of Synapses

The nectin-afadin system is a novel cell-cell adhesion system that organizes adherens junctions cooperatively with the cadherin-catenin system in epithelial cells. Nectin is an immunoglobulin-like adhesion molecule, and afadin is an actin filament-binding protein that connects nectin to the actin cy...

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Veröffentlicht in:	The Journal of cell biology 2002-02, Vol.156 (3), p.555-565
Hauptverfasser:	Mizoguchi, Akira, Nakanishi, Hiroyuki, Kimura, Kazushi, Matsubara, Kaho, Ozaki-Kuroda, Kumi, Katata, Tatsuo, Honda, Tomoyuki, Kiyohara, Yoshimoto, Heo, Kyun, Higashi, Mikito, Tsutsumi, Tomonari, Sonoda, Satomi, Ide, Chizuka, Takai, Yoshimi
Format:	Artikel
Sprache:	eng
Schlagworte:	Adherens junctions Adherens Junctions - drug effects Adherens Junctions - metabolism Adherens Junctions - ultrastructure Animals Cadherins Cell Adhesion - drug effects Cell Adhesion - physiology Cell Adhesion Molecules - antagonists & inhibitors Cell Adhesion Molecules - metabolism Cell Differentiation - drug effects Cell Differentiation - physiology Dendrites Dendrites - metabolism Dendrites - ultrastructure Dose-Response Relationship, Drug Epithelial cells Fetus Hippocampus Immunohistochemistry Kinesin Microfilament Proteins - metabolism Microscopy Microscopy, Electron Mossy Fibers, Hippocampal - embryology Mossy Fibers, Hippocampal - metabolism Mossy Fibers, Hippocampal - ultrastructure Myosins Nectins Neurons Protein Structure, Tertiary - physiology Pyramidal cells Pyramidal Cells - metabolism Pyramidal Cells - ultrastructure Rats Receptors Synapses Synapses - drug effects Synapses - metabolism Synapses - ultrastructure Synaptic Membranes - metabolism Synaptic Membranes - ultrastructure Synaptophysin - pharmacology Viral Envelope Proteins - pharmacology
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