Hyaluronan-CD44 Interaction Hampers Migration of Osteoclast-Like Cells by Down-Regulating MMP-9

Osteoclast (OC) precursors migrate to putative sites of bone resorption to form functionally active, multinucleated cells. The preOC FLG 29.1 cells, known to be capable of irreversibly differentiating into multinucleated OC-like cells, displayed several features of primary OCs, including expression...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The Journal of cell biology 2002-09, Vol.158 (6), p.1133-1144
Hauptverfasser:	Spessotto, Paola, Rossi, Francesca Maria, Degan, Massimo, Di Francia, Raffaele, Perris, Roberto, Colombatti, Alfonso, Gattei, Valter
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies, Monoclonal - pharmacology Bones Cell Adhesion Cell Adhesion Molecules - metabolism Cell Count Cell lines Cell membranes Cell motility Cell Movement Cells Cells, Cultured Cellular biology Dipeptides - pharmacology Down-Regulation Enzymes Extracellular Matrix - metabolism Humans Hyaluronan Receptors - metabolism Hyaluronan Receptors - physiology Hyaluronic Acid - metabolism Integrins Matrix Metalloproteinase 9 - metabolism Metalloendopeptidases - antagonists & inhibitors Metalloendopeptidases - genetics Oligonucleotides, Antisense - pharmacology Osteoclasts - cytology Osteoclasts - physiology Protease Inhibitors - pharmacology Receptors Stem cells Stromal cells Tissue Inhibitor of Metalloproteinase-1 - pharmacology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!