Regional dopamine transporter gene expression in the substantia nigra from control and Parkinson’s disease brains

OBJECTIVE To test the hypothesis that differential regional dopamine transporter (DAT) gene expression may underlie the selective vulnerability of certain nigral dopaminergic neurons in Parkinson’s disease, DAT mRNA expression was examined in neuronal subpopulations of human postmortem ventral mesen...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of neurology, neurosurgery and psychiatry neurosurgery and psychiatry, 1998-08, Vol.65 (2), p.164-169
Hauptverfasser:	Counihan, Timothy J, Penney, John B
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over amine transporter Biological and medical sciences Brain Carrier Proteins - genetics Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases Dopamine Dopamine Plasma Membrane Transport Proteins Female Gene expression Gene Expression - physiology Histology Humans in situ hybridisation In Situ Hybridization Male Medical sciences Membrane Glycoproteins Membrane Transport Proteins mesencephalon Middle Aged Nerve Tissue Proteins Neurology Neurons - pathology Parkinson Disease - genetics Parkinson Disease - pathology Parkinson's disease parkinsonism Patients Polymerase Chain Reaction Reference Values RNA polymerase RNA Probes RNA, Messenger - genetics Substantia Nigra - pathology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!