Differential Expression of Lumican and Fibromodulin Regulate Collagen Fibrillogenesis in Developing Mouse Tendons

Collagen fibrillogenesis is finely regulated during development of tissue-specific extracellular matrices. The role(s) of a leucine-rich repeat protein subfamily in the regulation of fibrillogenesis during tendon development were defined. Lumican-, fibromodulin-, and double-deficient mice demonstrat...

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Veröffentlicht in:	The Journal of cell biology 2000-11, Vol.151 (4), p.779-787
Hauptverfasser:	Ezura, Yoichi, Chakravarti, Shukti, Oldberg, Åke, Chervoneva, Inna, Birk, David E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging Animals Animals, Newborn Carrier Proteins - genetics Carrier Proteins - physiology Cellular biology Chondroitin Sulfate Proteoglycans - deficiency Chondroitin Sulfate Proteoglycans - genetics Chondroitin Sulfate Proteoglycans - physiology Collagen - genetics Collagen - physiology Collagen - ultrastructure Collagens Developmental biology Embryonic and Fetal Development Extracellular Matrix Proteins fibrillogenesis Fibromodulin Flexors Gene Expression Regulation, Developmental Keratan Sulfate - deficiency Keratan Sulfate - genetics Keratan Sulfate - physiology Lumican Mice Mice, Knockout Original Phenotype Phenotypes Physiological regulation Proteins Proteoglycans Solar fibrils Tendons Tendons - embryology Tendons - growth & development Tendons - physiology
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