Adhesion between cells, diffusion of growth factors, and elasticity of the AER produce the paddle shape of the chick limb

A central question in developmental biology is how cells interact to organize into tissues? In this paper, we study the role of mesenchyme-ectoderm interaction in the growing chick limb bud using Glazier and Graner's cellular Potts model, a grid-based stochastic framework designed to simulate c...

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Veröffentlicht in:	Physica A 2007, Vol.373, p.521-532
Hauptverfasser:	Popławski, Nikodem J., Swat, Maciej, Scott Gens, J., Glazier, James A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Apical ectodermal ridge Cell adhesion Cellular Potts model Chick limb growth CompuCell3D Fibroblast growth factor
Online-Zugang:	Volltext
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