Life-history traits drive the evolutionary rates of mammalian coding and noncoding genomic elements

A comprehensive phylogenetic framework is indispensable for investigating the evolution of genomic features in mammals as a whole, and particularly in humans. Using the ENCODE sequence data, we estimated mammalian neutral evolutionary rates and selective pressures acting on conserved coding and nonc...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2007-12, Vol.104 (51), p.20443-20448
Hauptverfasser:	Nikolaev, Sergey I, Montoya-Burgos, Juan I, Popadin, Konstantin, Parand, Leila, Margulies, Elliott H, Antonarakis, Stylianos E
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological Sciences Chimpanzees Conserved Sequence Databases, Genetic Deoxyribonucleic acid DNA DNA, Intergenic - genetics Evolution Evolution, Molecular Evolutionary biology Genetic Code Genetic mutation Genome - genetics Genome, Human - genetics Genomes Genomics Humans Linear regression Mammals Phylogenetics Population size Primates Selection, Genetic Sequence Analysis, DNA
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!