Neogenesis of Cerebellar Purkinje Neurons from Gene-Marked Bone Marrow Cells in vivo

The versatility of stem cells has only recently been fully recognized. There is evidence that upon adoptive bone marrow (BM) transplantation (BMT), donor-derived cells can give rise to neuronal phenotypes in the brains of recipient mice. Yet only few cells with the characteristic shape of neurons we...

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Veröffentlicht in:	The Journal of cell biology 2001-11, Vol.155 (5), p.733-738
Hauptverfasser:	Priller, Josef, Persons, Derek A., Klett, Francisco F., Kempermann, Gerd, Kreutzberg, Georg W., Dirnagl, Ulrich
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bone marrow Bone marrow cells Bone Marrow Cells - physiology Bone Marrow Cells - ultrastructure Bone Marrow Transplantation Brain Cell Transplantation Cells Cerebellum Cerebellum - cytology Flow Cytometry Genes Green Fluorescent Proteins Hematopoietic Stem Cell Transplantation Luminescent Proteins - genetics Luminescent Proteins - metabolism Male Mice Mice, Inbred C57BL Microscopy, Confocal - methods Microscopy, Immunoelectron Neural stem cells Neurons Purkinje cells Purkinje Cells - cytology Purkinje Cells - physiology Purkinje Cells - ultrastructure Recombinant Fusion Proteins - metabolism Retroviridae - physiology Stem Cell Transplantation Stem cells Stem Cells - physiology Transduction, Genetic Transplantation Transplantation Chimera Transplantation, Isogeneic
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