molecular specificity code for the three mammalian KDEL receptors

AC-terminal KDEL-like motif prevents secretion of soluble endoplasmic reticulum (ER)-resident proteins. This motif interacts with KDEL receptors localized in the intermediate compartment and Golgi apparatus. Such binding triggers retrieval back to the ER via a coat protein I-dependent pathway. To da...

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Veröffentlicht in:	The Journal of cell biology 2007-12, Vol.179 (6), p.1193-1204
Hauptverfasser:	Raykhel, Irina, Alanen, Heli, Salo, Kirsi, Jurvansuu, Jaana, Nguyen, Van Dat, Latva-Ranta, Maria, Ruddock, Lloyd
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Motifs Animals Antibodies Biochemistry Cells Cercopithecus aethiops Cloning, Molecular COS Cells Endoplasmic Reticulum - metabolism Fluorescence Fluorescent antibody techniques Genes, Reporter Golgi Apparatus - metabolism HeLa Cells Humans Mammals Molecular Sequence Data Molecules Plasmids Protein Sorting Signals Proteins Receptors Receptors, Peptide - analysis Receptors, Peptide - chemistry Secretory pathway Sequence Alignment Social interaction Transfection
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