A Molecular Mechanism of Integrin Crosstalk: αvβ3 Suppression of Calcium/Calmodulin-dependent Protein Kinase II Regulates α5β1 Function

Many cells express more than one integrin receptor for extracellular matrix, and in vivo these receptors may be simultaneously engaged. Ligation of one integrin may influence the behavior of others on the cell, a phenomenon we have called integrin crosstalk. Ligation of the integrin αvβ3 inhibits bo...

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Veröffentlicht in:The Journal of cell biology 1999-05, Vol.145 (4), p.889-897
Hauptverfasser: Blystone, Scott D., Slater, Suzanne E., Williams, Matthew P., Crow, Michael T., Brown, Eric J.
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Sprache:eng
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