CRM1-Mediated Recycling of Snurportin 1 to the Cytoplasm

Importin β is a major mediator of import into the cell nucleus. Importin β binds cargo molecules either directly or via two types of adapter molecules, importin α, for import of proteins with a classical nuclear localization signal (NLS), or snurportin 1, for import of m3G-capped U snRNPs. Both adap...

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Veröffentlicht in:	The Journal of cell biology 1999-04, Vol.145 (2), p.255-264
Hauptverfasser:	Paraskeva, Efrosyni, Izaurralde, Elisa, Bischoff, F. Ralf, Huber, Jochen, Kutay, Ulrike, Hartmann, Enno, Lührmann, Reinhard, Görlich, Dirk
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Binding Sites Carrier Proteins - metabolism Cell Nucleus - metabolism Cellular biology Chromatography, Affinity Cytoplasm Cytoplasm - metabolism Escherichia coli Exportin 1 Protein Female Freight HeLa Cells Humans Imports Karyopherins Kinetics Messenger RNA Models, Biological Nuclear proteins Nuclear Proteins - isolation & purification Nuclear Proteins - metabolism Oocytes - physiology Proteins Receptors Receptors, Cytoplasmic and Nuclear - isolation & purification Receptors, Cytoplasmic and Nuclear - metabolism Recombinant Proteins - isolation & purification Recombinant Proteins - metabolism Regular Ribonucleoproteins, Small Nuclear - metabolism RNA RNA Cap-Binding Proteins Signal Transduction Small nuclear ribonucleoproteins Small nuclear RNA Transcription Factors - metabolism Xenopus laevis
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