Spatial and Temporal Dynamics of DNA Replication Sites in Mammalian Cells

Fluorescence microscopic analysis of newly replicated DNA has revealed discrete granular sites of replication (RS). The average size and number of replication sites from early to mid S-phase suggest that each RS contains numerous replicons clustered together. We are using fluorescence laser scanning...

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Veröffentlicht in:	The Journal of cell biology 1998-12, Vol.143 (6), p.1415-1425
Hauptverfasser:	Ma, Hong, Samarabandu, Jagath, Devdhar, Rekandu S., Acharya, Raj, Cheng, Ping-chin, Meng, Chunling, Berezney, Ronald
Format:	Artikel
Sprache:	eng
Schlagworte:	3T3 Cells Animals Cell cycle Cell Cycle - physiology Cell nucleus Cells Chromatin Chromosomes Chromosomes - genetics Chromosomes - ultrastructure Deoxyribonucleic acid DNA DNA - biosynthesis DNA - chemistry DNA - genetics DNA Replication G1 Phase Kinetics Mammals Mice Microscopy, Confocal Reed Sternberg cells Replicon Replicon - genetics S Phase Time Factors
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