A Role for Tissue Factor in Cell Adhesion and Migration Mediated by Interaction with Actin-Binding Protein 280

Tissue factor (TF), the protease receptor initiating the coagulation system, functions in vascular development, angiogenesis, and tumor cell metastasis by poorly defined molecular mechanisms. We demonstrate that immobilized ligands for TF specifically support cell adhesion, migration, spreading, and...

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Veröffentlicht in:	The Journal of cell biology 1998-03, Vol.140 (5), p.1241-1253
Hauptverfasser:	Ott, Ilka, Fischer, Edgar G., Miyagi, Yohei, Mueller, Barbara M., Ruf, Wolfram
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies Binding Sites Cell adhesion Cell Adhesion - physiology Cell Adhesion Molecules - metabolism Cell Line, Transformed Cell Movement - physiology Cells Cellular biology Chemical Precipitation Chimeras Contractile Proteins - metabolism Cytoplasm - metabolism Endothelial cells Fibrosis Filamins Focal Adhesion Kinase 1 Focal Adhesion Protein-Tyrosine Kinases Genes Humans Ligands Microfilament Proteins - metabolism Phosphorylation Protein-Tyrosine Kinases - metabolism Proteins Receptors Thromboplastin - metabolism Tumor Cells, Cultured Tumors
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