Inhibition of Endosome Function in CHO Cells Bearing a Temperature-Sensitive Defect in the Coatomer (COPI) Component ε-COP

Recent evidence has suggested that subunits of the coatomer protein (COPI) complexes are functionally associated with endosomes in mammalian cells. We now provide genetic evidence that COPI plays a role in endocytosis in intact cells. The ldlF mutant CHO cell line bears a temperature-sensitive defec...

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