Do neuroleptic drugs hasten cognitive decline in dementia? Prospective study with necropsy follow up

Abstract Objective: To investigate the contribution of neuroleptic drugs to cognitive decline in dementia. Design: Two year prospective, longitudinal study consisting of interviews every four months, with necropsy follow up. Setting: Community settings in Oxfordshire. Subjects: 71 subjects with deme...

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Veröffentlicht in:	BMJ 1997-01, Vol.314 (7076), p.266-270
Hauptverfasser:	McShane, Rupert, Keene, Janet, Gedling, Kathy, Fairburn, Christopher, Jacoby, Robin, Hope, Tony
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Alzheimers disease Antipsychotic agents Antipsychotic Agents - adverse effects Autopsy Circadian rhythm Cognition Disorders - chemically induced Cognition Disorders - pathology Dementia Dementia - complications Dementia - pathology Female Follow-Up Studies Geriatric psychiatry Hallucination Hope Humans Lewy bodies Male Mental Disorders - drug therapy Mental Disorders - etiology Mental Disorders - pathology Older adults Parkinson Disease, Secondary - pathology Pathology Prospective Studies Regression Analysis
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