Biological Differences in rAAV Transduction of Airway Epithelia in Humans and in Old World Non-human Primates

Non-human primates (NHPs) are considered to be among the most relevant animal models for pre-clinical testing of human therapies, on the basis of their close evolutionary relatedness to humans in terms of organ cell biology and physiology. In this study, we sought to investigate whether NHP models a...

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Veröffentlicht in:Molecular therapy 2007-12, Vol.15 (12), p.2114-2123
Hauptverfasser: Liu, Xiaoming, Luo, Meihui, Trygg, Cyndi, Yan, Ziying, Lei-Butters, Diana CM, Smith, Carolina I, Fischer, Anne C, Munson, Keith, Guggino, William B, Bunnell, Bruce A, Engelhardt, John F
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Sprache:eng
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