E-Cadherin and APC Compete for the Interaction with β-Catenin and the Cytoskeleton

β-Catenin is involved in the formation of adherens junctions of mammalian epithelia. It interacts with the cell adhesion molecule E-cadherin and also with the tumor suppressor gene product APC, and the Drosophila homologue of β-catenin, armadillo, mediates morphogenetic signals. We demonstrate here...

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Veröffentlicht in:	The Journal of cell biology 1994-12, Vol.127 (6), p.2061-2069
Hauptverfasser:	Hülsken, Jörg, Birchmeier, Walter, Behrens, Jürgen
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenomatous Polyposis Coli Protein alpha Catenin Amino Acid Sequence Antibodies Base Sequence beta Catenin Cadherins Cadherins - genetics Cadherins - isolation & purification Cadherins - metabolism Catenins Cell adhesion Cell lines Cells Cells, Cultured Cellular biology Complementary DNA Cytoskeletal Proteins - genetics Cytoskeletal Proteins - isolation & purification Cytoskeletal Proteins - metabolism Cytoskeleton - metabolism Desmoplakins Embryonic cells Epithelial cells Fluorescent Antibody Technique gamma Catenin Genes Intercellular Junctions Models, Molecular Molecular Sequence Data Mutagenesis, Site-Directed Neurons Precipitin Tests Protein Binding Recombinant Proteins - metabolism Trans-Activators Tumors
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