CD48 is a counter-receptor for mouse CD2 and is involved in T cell activation

CD2 is an intercellular adhesion molecule that has been implicated in T cell activation and differentiation both in humans and mice. Although the ligand for human CD2 has been defined as LFA-3, that for murine CD2 has not been identified yet. To identify the ligand for mouse CD2, we generated a chim...

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Veröffentlicht in:	The Journal of experimental medicine 1992-11, Vol.176 (5), p.1241-1249
Hauptverfasser:	KATO, K, KOYANAGI, M, OKADA, H, TAKANASHI, T, YEE WAH WONG, WILLIAMS, A. F, OKUMURA, K, YAGITA, H
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Monoclonal - immunology Antigens, CD - physiology Antigens, Differentiation, T-Lymphocyte - metabolism Base Sequence Biological and medical sciences CD2 Antigens CD48 Antigen CD58 Antigens Cricetinae Fundamental and applied biological sciences. Psychology Fundamental immunology Immunobiology Ligands Lymphocyte Activation Lymphoid cells: ontogeny, maturation, markers, receptors, circulation and recirculation Male Membrane Glycoproteins - physiology Mice Molecular Sequence Data Rats Receptors, Immunologic - metabolism Recombinant Fusion Proteins - metabolism T-Lymphocytes - immunology
Online-Zugang:	Volltext
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