The cytoplasmic domain of the integrin lymphocyte function-associated antigen 1 beta subunit: sites required for binding to intercellular adhesion molecule 1 and the phorbol ester-stimulated phosphorylation site

We have defined the regions of the cytoplasmic domain of the leukocyte integrin lymphocyte function-associated antigen 1 (LFA-1) that are required for active binding of its extracellular domain to intercellular adhesion molecule 1 (ICAM-1). The NH2-terminal 28 amino acids in the cytoplasmic domain a...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	The Journal of experimental medicine 1991-11, Vol.174 (5), p.1227-1238
Hauptverfasser:	Hibbs, M L, Jakes, S, Stacker, S A, Wallace, R W, Springer, T A
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Cell Adhesion Molecules - metabolism Cytoplasm - chemistry Humans Intercellular Adhesion Molecule-1 Lymphocyte Function-Associated Antigen-1 - chemistry Lymphocyte Function-Associated Antigen-1 - metabolism Molecular Sequence Data Phosphorylation Structure-Activity Relationship Tetradecanoylphorbol Acetate - pharmacology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!