Fibrinolytic response to tumor necrosis factor in healthy subjects

Tumor necrosis factor (TNF) may be involved in the disturbance of the procoagulant-fibrinolytic balance in septicemia, leading to microvascular thrombosis. To assess the dynamics of the fibrinolytic response to TNF in humans, we performed a crossover saline-controlled study in six healthy men, inves...

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Veröffentlicht in:	The Journal of experimental medicine 1991-09, Vol.174 (3), p.729-732
Hauptverfasser:	VAN DER POLL, T, LEVI, M, BÜLLER, H. R, VAN DEVENTER, S. J. H, DE BOER, J. P, HACK, C. E, TEN CATE, J. W
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult alpha-Macroglobulins - metabolism Biological and medical sciences Blood coagulation. Blood cells Enzyme Activation Fibrinolysin - metabolism Fibrinolysis Fundamental and applied biological sciences. Psychology General aspects, investigation methods, hemostasis, fibrinolysis Humans Male Molecular and cellular biology Plasminogen - metabolism Plasminogen Inactivators - blood Recombinant Proteins Tumor Necrosis Factor-alpha - pharmacology
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