Terminal Short Arm Domains of Basement Membrane Laminin Are Critical for Its Self-Assembly

Laminin self-assembles into large polymers by a cooperative two-step calcium-dependent mechanism (Yurchenco, P. D., E. C. Tsilibary, A. S. Charonis, and H. Furthmayr. 1985. J. Biol. Chem. 260:7636-7644). The domain specificity of this process was investigated using defined proteolytically generated...

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Veröffentlicht in:	The Journal of cell biology 1990-03, Vol.110 (3), p.825-832
Hauptverfasser:	Schittny, Johannes C., Yurchenco, Peter D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical, structural and metabolic biochemistry Basement membrane Basement Membrane - metabolism basement membranes Biological and medical sciences Calcium Chromatography Chromatography, Affinity Collagens Fundamental and applied biological sciences. Psychology Gels Globules Glycoproteins Kinetics Laminin - metabolism Laminin - ultrastructure Macromolecular Substances Memory interference Microscopy, Electron Models, Molecular Peptide Fragments - isolation & purification Polymerization Polymers Protein Conformation Proteins Turbidity
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