Immunochemical Characterization of Three Components of the Hemidesmosome and Their Expression in Cultured Epithelial Cells

Treatment of bovine tongue mucosa with 1 M KCl induced a split in the lamina densa of the basement membrane zone (BMZ). The epithelium was then separated from the underlying connective tissue. Electron microscopic analysis of the stripped epithelium revealed that hemidesmosomes and their associated...

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Veröffentlicht in:	The Journal of cell biology 1989-12, Vol.109 (6), p.3377-3390
Hauptverfasser:	Klatte, David H., Kurpakus, Michelle A., Grelling, Kent A., Jonathan C. R. Jones
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies Antibodies, Monoclonal Antigens Autoantibodies Autoantibodies - immunology Basement Membrane - ultrastructure Biological and medical sciences Cattle Cell structures and functions Cells, Cultured Cultured cells Cytoskeleton, cytoplasm. Intracellular movements Desmosomes Desmosomes - immunology Desmosomes - metabolism Desmosomes - ultrastructure Electrophoresis, Polyacrylamide Gel Epithelial cells Epithelium Epithelium - immunology Epithelium - metabolism Fluorescent Antibody Technique Fluorescent antibody techniques Fundamental and applied biological sciences. Psychology Hemidesmosomes Humans Intermediate Filaments - metabolism Mice Molecular and cellular biology Mucous Membrane - ultrastructure Pemphigoid, Bullous - immunology Protein Biosynthesis Proteins - immunology Tongue - ultrastructure Ungulates
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