Characterization of a Renal Tubular Epithelial Cell Line Which Secretes the Autologous Target Antigen of Autoimmune Experimental Interstitial Nephritis

Proximal tubular epithelial cells from mice which develop autoimmune interstitial nephritis were found to express the nephritogenic target antigen, 3M-1. Anti-3M-1 mAbs (α3M-1-Ab) were used to positively select for 3M-1-secreting tubular epithelium and, after stabilization in culture, this new cell...

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Veröffentlicht in:	The Journal of cell biology 1988-10, Vol.107 (4), p.1359-1368
Hauptverfasser:	Haverty, Thomas P., Kelly, Carolyn J., Hines, William H., Amenta, Peter S., Watanabe, Melanie, Harper, Robert A., Kefalides, Nicholas A., Neilson, Eric G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies Antigens Autoantigens - immunology Autoimmune Diseases - immunology Autoimmunity (experimental aspects and models) Biological and medical sciences Cell Division Cell growth Cell lines Cells Collagens Cultured cells Epithelial cells Epithelium ErbB Receptors - metabolism Extracellular Matrix - physiology Fundamental and applied biological sciences. Psychology Fundamental immunology Interstitial nephritis Kidney Tubules - cytology Kidney Tubules - immunology Kidney Tubules - metabolism Mice Microscopy, Electron Nephritis, Interstitial - immunology T lymphocytes
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