Clogging of the Glomerular Basement Membrane

The negative charges of the sulfated glycosaminoglycans (GAGs) of the glomerular basement membrane (GBM) were differentially neutralized by perfusion with high molarity buffers in order to determine whether or not these charges protect the GBM from being clogged by circulating plasma macromolecules....

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Veröffentlicht in:	The Journal of cell biology 1982-05, Vol.93 (2), p.489-494
Hauptverfasser:	Kanwar, Yashpal S., Rosenzweig, Lionel J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Basement membrane Basement Membrane - physiology Basement Membrane - ultrastructure Cell Membrane Permeability Ferritins Glomerular Filtration Rate Glycosaminoglycans Glycosaminoglycans - physiology Insulin Insulin - metabolism Kidney Glomerulus - blood supply Kidney Glomerulus - physiology Kidney Glomerulus - ultrastructure Kidneys Macromolecules Male Models, Biological Perfusion Proteins Rapid Communications Rats Serum Albumin, Bovine Sulfates
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