Favorable Effects of Weak Acids on Negative-Ion Electrospray Ionization Mass Spectrometry

Despite widespread use in pharmacokinetic, drug metabolism, and pesticide residue studies, little is known about the factors governing response during reversed-phase liquid chromatography coupled with negative-ion electrospray ionization (ESI-) mass spectrometry. We examined the effects of various m...

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Veröffentlicht in:	Analytical chemistry (Washington) 2004-02, Vol.76 (3), p.839-847
Hauptverfasser:	Wu, Zengru, Gao, Wenqing, Phelps, Mitch A., Wu, Di, Miller, Duane D., Dalton, James T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acids Acids - chemistry Analytical chemistry Anions - chemistry Chemical compounds Chemistry Chromatographic methods and physical methods associated with chromatography Chromatography, High Pressure Liquid - methods Estrogen Receptor Modulators - analysis Estrogen Receptor Modulators - chemistry Exact sciences and technology Formaldehyde - chemistry Molecular Structure Other chromatographic methods Protons Salt Salts - chemistry Spectrometric and optical methods Spectrometry, Mass, Electrospray Ionization - methods Spectrum analysis Trifluoroethanol - chemistry
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