Monomer-dimer dynamics and distribution of GPI-anchored uPAR are determined by cell surface protein assemblies

To search for functional links between glycosylphosphatidylinositol (GPI) protein monomer-oligomer exchange and membrane dynamics and confinement, we studied urokinase plasminogen activator (uPA) receptor (uPAR), a GPI receptor involved in the regulation of cell adhesion, migration, and proliferatio...

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Veröffentlicht in:	The Journal of cell biology 2007-12, Vol.179 (5), p.1067-1082
Hauptverfasser:	Caiolfa, Valeria R, Zamai, Moreno, Malengo, Gabriele, Andolfo, Annapaola, Madsen, Chris D, Sutin, Jason, Digman, Michelle A, Gratton, Enrico, Blasi, Francesco, Sidenius, Nicolai
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell adhesion Cell adhesion & migration Cell Line Cell lines Cell Membrane - metabolism Cell membranes Diffusion Dimerization Dimers Endocytosis Extracellular Matrix - metabolism Fluorescence Fluorescence Resonance Energy Transfer Glycosylphosphatidylinositols - metabolism HEK293 cells Humans Membranes Models, Biological Molecules P branes Pixels Plasminogen Activator Inhibitor 1 - metabolism Protein Binding Protein Transport Proteins Receptors Receptors, Cell Surface - metabolism Receptors, Urokinase Plasminogen Activator Recycling Serum Studies Vitronectin - metabolism
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