Multiple conserved regulatory elements with overlapping functions determine Sox10 expression in mouse embryogenesis

Expression and function of the transcription factor Sox10 is predominant in neural crest cells, its derivatives and in oligodendrocytes. To understand how Sox10 expression is regulated during development, we analysed the potential of evolutionary conserved non-coding sequences in the Sox10 genomic r...

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Veröffentlicht in:	Nucleic acids research 2007-10, Vol.35 (19), p.6526-6538
Hauptverfasser:	Werner, Torsten, Hammer, Alexander, Wahlbuhl, Mandy, Bösl, Michael R., Wegner, Michael
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Base Sequence Binding Sites Birds - genetics Cell Line Conserved Sequence DNA-Binding Proteins - genetics DNA-Binding Proteins - metabolism Embryo, Mammalian - metabolism Embryonic Development - genetics Enhancer Elements, Genetic Gene Expression Regulation, Developmental Genomics High Mobility Group Proteins - genetics High Mobility Group Proteins - metabolism Humans Mammals - genetics Mice Mice, Transgenic SOXE Transcription Factors Transcription Factors - genetics Transcription Factors - metabolism
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