Dynamic interactions within sub-complexes of the H/ACA pseudouridylation guide RNP

H/ACA RNP complexes change uridines to pseudouridines in target non-coding RNAs in eukaryotes and archaea. H/ACA RNPs are comprised of a guide RNA and four essential proteins: Cbf5 (pseudouridine synthase), L7Ae, Gar1 and Nop10 in archaea. The guide RNA captures the target RNA via two antisense elem...

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Veröffentlicht in:	Nucleic acids research 2007-09, Vol.35 (18), p.6196-6206
Hauptverfasser:	Youssef, Osama A, Terns, Rebecca M, Terns, Michael P
Format:	Artikel
Sprache:	eng
Schlagworte:	Archaea Archaeal Proteins - metabolism Base Sequence Binding Sites Conserved Sequence Hydro-Lyases - metabolism Molecular Biology Molecular Sequence Data Nucleic Acid Conformation Pseudouridine - metabolism Pyrococcus furiosus - enzymology Ribonucleoproteins, Small Nucleolar - metabolism RNA, Archaeal - chemistry RNA, Archaeal - metabolism RNA, Guide - chemistry RNA, Guide - metabolism
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