Mammalian cilia function is independent of the polymeric state of tubulin glycylation

Polyglycylation is a polymeric post‐translational modification of tubulin that is ubiquitous and widely present in cilia and flagella. It consists of the addition of highly variable numbers of glycyl residues as side chains onto the γ carboxyl group of specific glutamyl residues at the C‐termini of...

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Veröffentlicht in:	Cell motility and the cytoskeleton 2007-11, Vol.64 (11), p.847-855
Hauptverfasser:	Dossou, Starlette J. Y., Bré, Marie-Hélène, Hallworth, Richard
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Division - physiology Cell Movement - physiology Cells, Cultured cilia Cilia - metabolism Cilia - physiology Cilia - ultrastructure Female Fluorescent Antibody Technique - methods Gerbillinae Glutamic Acid - chemistry Glutamic Acid - metabolism Glutamic Acid - physiology Male Mammals Mice Mice, Inbred C57BL Microscopy, Confocal - methods monoglycylation Polyglutamic Acid - chemistry Polyglutamic Acid - metabolism Polyglutamic Acid - physiology polyglycylation post-translational modification Protein Processing, Post-Translational tubuli Tubulin - chemistry Tubulin - metabolism
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