Vitamin D deficiency: prevention or treatment?

Background: Vitamin D deficiency is a chronic condition which contributes to general ill health and seems to be re-emerging in our catchment area since funding of vitamin D supplementation by Primary Care Trusts ceased. This study aims to verify this situation and to assess the cost effectiveness of...

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Veröffentlicht in:Archives of disease in childhood 2006-12, Vol.91 (12), p.1011-1014
Hauptverfasser: Zipitis, C S, Markides, G A, Swann, I L
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container_title Archives of disease in childhood
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creator Zipitis, C S
Markides, G A
Swann, I L
description Background: Vitamin D deficiency is a chronic condition which contributes to general ill health and seems to be re-emerging in our catchment area since funding of vitamin D supplementation by Primary Care Trusts ceased. This study aims to verify this situation and to assess the cost effectiveness of reintroducing vitamin D supplementation in the Burnley Health Care NHS Trust. Methods: Vitamin D deficient patients presenting between January 1994 and May 2005 were identified and data retrospectively collected from their case notes. The cost of treatment and the theoretical cost of primary prevention for the Trust population were calculated using previous and current DoH guidelines. Results: Fourteen patients were identified, of whom 86% presented in the last 5 years and 93% were of Asian origin. The incidence of vitamin D deficiency for our population is 1 in 923 children overall and 1 in 117 in children of Asian origin. The average cost of treatment for each such child is £2500, while the theoretical cost of prevention of vitamin D deficiency in the Asian population through primary prevention according to COMA guidance is £2400 per case. Conclusions: Vitamin D deficiency is re-emerging in our Trust. The overwhelming majority of our patients are of Asian origin. The cost of primary prevention for this high risk population compares favourably both medically and financially with treatment of established disease. We suggest that Primary Care Trusts provide funds for vitamin D supplementation of Asian children for at least the first 2 years of life.
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This study aims to verify this situation and to assess the cost effectiveness of reintroducing vitamin D supplementation in the Burnley Health Care NHS Trust. Methods: Vitamin D deficient patients presenting between January 1994 and May 2005 were identified and data retrospectively collected from their case notes. The cost of treatment and the theoretical cost of primary prevention for the Trust population were calculated using previous and current DoH guidelines. Results: Fourteen patients were identified, of whom 86% presented in the last 5 years and 93% were of Asian origin. The incidence of vitamin D deficiency for our population is 1 in 923 children overall and 1 in 117 in children of Asian origin. The average cost of treatment for each such child is £2500, while the theoretical cost of prevention of vitamin D deficiency in the Asian population through primary prevention according to COMA guidance is £2400 per case. Conclusions: Vitamin D deficiency is re-emerging in our Trust. The overwhelming majority of our patients are of Asian origin. The cost of primary prevention for this high risk population compares favourably both medically and financially with treatment of established disease. We suggest that Primary Care Trusts provide funds for vitamin D supplementation of Asian children for at least the first 2 years of life.</description><identifier>ISSN: 0003-9888</identifier><identifier>EISSN: 1468-2044</identifier><identifier>DOI: 10.1136/adc.2006.098467</identifier><identifier>PMID: 16945992</identifier><identifier>CODEN: ADCHAK</identifier><language>eng</language><publisher>London: BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health</publisher><subject>25-hydroxycholecalciferol ; 25OHC ; Age ; alkaline phosphatase ; ALP ; Babies ; Biological and medical sciences ; Care and treatment ; Catchment areas ; Child, Preschool ; Coding ; COMA ; Committee on Medical Aspects of Food and Nutritional Policy ; cost-benefit ; Cystic fibrosis ; Demographics ; Department of Health ; Departments ; Dietary supplements ; DoH ; Drug Costs ; Female ; Humans ; hypocalcaemia ; Infant ; Infant, Newborn ; Male ; Medical sciences ; Metabolic diseases ; Miscellaneous ; Original ; Patients ; Pediatrics ; Population ; Pregnancy ; Prevention ; Prevention and actions ; Public health. Hygiene ; Public health. Hygiene-occupational medicine ; Radiation ; reference nutrient intake ; Retrospective Studies ; Rickets ; RNI ; treatment ; Trust departments ; Vitamin D ; Vitamin D - economics ; Vitamin D - therapeutic use ; Vitamin D deficiency ; Vitamin D Deficiency - drug therapy ; Vitamin D Deficiency - economics ; Vitamin D Deficiency - prevention &amp; control ; vitamin D supplementation ; Vitamin deficiency ; Young Children</subject><ispartof>Archives of disease in childhood, 2006-12, Vol.91 (12), p.1011-1014</ispartof><rights>Copyright 2006 Archives of Disease in Childhood</rights><rights>2007 INIST-CNRS</rights><rights>Copyright: 2006 Copyright 2006 Archives of Disease in Childhood</rights><rights>Copyright ©2006 BMJ Publishing Group &amp; Royal College of Paediatrics and Child Health</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b560t-86764ea57ad66df29da8f29e75b1ada7fa2127983ae24ecf5697313656fef7e3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttp://adc.bmj.com/content/91/12/1011.full.pdf$$EPDF$$P50$$Gbmj$$H</linktopdf><linktohtml>$$Uhttp://adc.bmj.com/content/91/12/1011.full$$EHTML$$P50$$Gbmj$$H</linktohtml><link.rule.ids>114,115,230,314,727,780,784,885,3194,23569,27922,27923,53789,53791,77370,77401</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&amp;idt=18275305$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16945992$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Zipitis, C S</creatorcontrib><creatorcontrib>Markides, G A</creatorcontrib><creatorcontrib>Swann, I L</creatorcontrib><title>Vitamin D deficiency: prevention or treatment?</title><title>Archives of disease in childhood</title><addtitle>Arch Dis Child</addtitle><description>Background: Vitamin D deficiency is a chronic condition which contributes to general ill health and seems to be re-emerging in our catchment area since funding of vitamin D supplementation by Primary Care Trusts ceased. This study aims to verify this situation and to assess the cost effectiveness of reintroducing vitamin D supplementation in the Burnley Health Care NHS Trust. Methods: Vitamin D deficient patients presenting between January 1994 and May 2005 were identified and data retrospectively collected from their case notes. The cost of treatment and the theoretical cost of primary prevention for the Trust population were calculated using previous and current DoH guidelines. Results: Fourteen patients were identified, of whom 86% presented in the last 5 years and 93% were of Asian origin. The incidence of vitamin D deficiency for our population is 1 in 923 children overall and 1 in 117 in children of Asian origin. The average cost of treatment for each such child is £2500, while the theoretical cost of prevention of vitamin D deficiency in the Asian population through primary prevention according to COMA guidance is £2400 per case. Conclusions: Vitamin D deficiency is re-emerging in our Trust. The overwhelming majority of our patients are of Asian origin. The cost of primary prevention for this high risk population compares favourably both medically and financially with treatment of established disease. We suggest that Primary Care Trusts provide funds for vitamin D supplementation of Asian children for at least the first 2 years of life.</description><subject>25-hydroxycholecalciferol</subject><subject>25OHC</subject><subject>Age</subject><subject>alkaline phosphatase</subject><subject>ALP</subject><subject>Babies</subject><subject>Biological and medical sciences</subject><subject>Care and treatment</subject><subject>Catchment areas</subject><subject>Child, Preschool</subject><subject>Coding</subject><subject>COMA</subject><subject>Committee on Medical Aspects of Food and Nutritional Policy</subject><subject>cost-benefit</subject><subject>Cystic fibrosis</subject><subject>Demographics</subject><subject>Department of Health</subject><subject>Departments</subject><subject>Dietary supplements</subject><subject>DoH</subject><subject>Drug Costs</subject><subject>Female</subject><subject>Humans</subject><subject>hypocalcaemia</subject><subject>Infant</subject><subject>Infant, Newborn</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Metabolic diseases</subject><subject>Miscellaneous</subject><subject>Original</subject><subject>Patients</subject><subject>Pediatrics</subject><subject>Population</subject><subject>Pregnancy</subject><subject>Prevention</subject><subject>Prevention and actions</subject><subject>Public health. Hygiene</subject><subject>Public health. Hygiene-occupational medicine</subject><subject>Radiation</subject><subject>reference nutrient intake</subject><subject>Retrospective Studies</subject><subject>Rickets</subject><subject>RNI</subject><subject>treatment</subject><subject>Trust departments</subject><subject>Vitamin D</subject><subject>Vitamin D - economics</subject><subject>Vitamin D - therapeutic use</subject><subject>Vitamin D deficiency</subject><subject>Vitamin D Deficiency - drug therapy</subject><subject>Vitamin D Deficiency - economics</subject><subject>Vitamin D Deficiency - prevention &amp; control</subject><subject>vitamin D supplementation</subject><subject>Vitamin deficiency</subject><subject>Young Children</subject><issn>0003-9888</issn><issn>1468-2044</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNqFkUuLFDEUhYMoTju6dicFoguhevKovFwoQ_vEwUFoRnAT0qlbbdqqpE2qB-ffm6aaaXXjJiHcL-eew0HoMcFzQpg4s62bU4zFHGvVCHkHzUgjVE1x09xFM4wxq7VS6gQ9yHmDMaFKsfvohAjdcK3pDM2v_GgHH6o3VQuddx6Cu3lZbRNcQxh9DFVM1ZjAjkN5v36I7nW2z_DocJ-i5bu3y8WH-uLy_cfF-UW94gKPtRJSNGC5tK0QbUd1a1U5QfIVsa2VnaWESq2YBdqA67jQkpU8XHTQSWCn6NUku92tBmhdWZ1sb7bJDzbdmGi9-XsS_HezjteGYsUwxUXg-UEgxZ87yKMZfHbQ9zZA3GUjFJGEqT349B9wE3cplGyGKKqolBSTQtUTtbY9GB9cDCP8Gl3se1iDKdEXl-accMW1kkoU_mziXYo5J-hurRNs9sWZUpzZF2em4sqPJ38mPvKHpgrw7ADY7GzfJRucz0euWOUM86NVn4vF27lNP0xZI7n5fLUwXz_xL5h902ZZ-BcTvxo2_3X5G57qu28</recordid><startdate>20061201</startdate><enddate>20061201</enddate><creator>Zipitis, C S</creator><creator>Markides, G A</creator><creator>Swann, I L</creator><general>BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health</general><general>BMJ</general><general>BMJ Publishing Group Ltd</general><general>BMJ Publishing Group LTD</general><general>BMJ Group</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>0-V</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88B</scope><scope>88E</scope><scope>88I</scope><scope>8A4</scope><scope>8AF</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>ALSLI</scope><scope>AN0</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>CJNVE</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9-</scope><scope>K9.</scope><scope>LK8</scope><scope>M0P</scope><scope>M0R</scope><scope>M0S</scope><scope>M1P</scope><scope>M2P</scope><scope>M7P</scope><scope>PQEDU</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20061201</creationdate><title>Vitamin D deficiency: prevention or treatment?</title><author>Zipitis, C S ; Markides, G A ; Swann, I L</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b560t-86764ea57ad66df29da8f29e75b1ada7fa2127983ae24ecf5697313656fef7e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>25-hydroxycholecalciferol</topic><topic>25OHC</topic><topic>Age</topic><topic>alkaline phosphatase</topic><topic>ALP</topic><topic>Babies</topic><topic>Biological and medical sciences</topic><topic>Care and treatment</topic><topic>Catchment areas</topic><topic>Child, Preschool</topic><topic>Coding</topic><topic>COMA</topic><topic>Committee on Medical Aspects of Food and Nutritional Policy</topic><topic>cost-benefit</topic><topic>Cystic fibrosis</topic><topic>Demographics</topic><topic>Department of Health</topic><topic>Departments</topic><topic>Dietary supplements</topic><topic>DoH</topic><topic>Drug Costs</topic><topic>Female</topic><topic>Humans</topic><topic>hypocalcaemia</topic><topic>Infant</topic><topic>Infant, Newborn</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Metabolic diseases</topic><topic>Miscellaneous</topic><topic>Original</topic><topic>Patients</topic><topic>Pediatrics</topic><topic>Population</topic><topic>Pregnancy</topic><topic>Prevention</topic><topic>Prevention and actions</topic><topic>Public health. Hygiene</topic><topic>Public health. Hygiene-occupational medicine</topic><topic>Radiation</topic><topic>reference nutrient intake</topic><topic>Retrospective Studies</topic><topic>Rickets</topic><topic>RNI</topic><topic>treatment</topic><topic>Trust departments</topic><topic>Vitamin D</topic><topic>Vitamin D - economics</topic><topic>Vitamin D - therapeutic use</topic><topic>Vitamin D deficiency</topic><topic>Vitamin D Deficiency - drug therapy</topic><topic>Vitamin D Deficiency - economics</topic><topic>Vitamin D Deficiency - prevention &amp; control</topic><topic>vitamin D supplementation</topic><topic>Vitamin deficiency</topic><topic>Young Children</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Zipitis, C S</creatorcontrib><creatorcontrib>Markides, G A</creatorcontrib><creatorcontrib>Swann, I L</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Social Sciences Premium Collection</collection><collection>ProQuest Central (Corporate)</collection><collection>Health &amp; Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Education Database (Alumni Edition)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>Education Periodicals</collection><collection>STEM Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central UK/Ireland</collection><collection>Social Science Premium Collection</collection><collection>British Nursing Database</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>BMJ Journals</collection><collection>ProQuest One Community College</collection><collection>Education Collection</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>Consumer Health Database (Alumni Edition)</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Education Database</collection><collection>Consumer Health Database</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Science Database</collection><collection>Biological Science Database</collection><collection>ProQuest One Education</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Archives of disease in childhood</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Zipitis, C S</au><au>Markides, G A</au><au>Swann, I L</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Vitamin D deficiency: prevention or treatment?</atitle><jtitle>Archives of disease in childhood</jtitle><addtitle>Arch Dis Child</addtitle><date>2006-12-01</date><risdate>2006</risdate><volume>91</volume><issue>12</issue><spage>1011</spage><epage>1014</epage><pages>1011-1014</pages><issn>0003-9888</issn><eissn>1468-2044</eissn><coden>ADCHAK</coden><abstract>Background: Vitamin D deficiency is a chronic condition which contributes to general ill health and seems to be re-emerging in our catchment area since funding of vitamin D supplementation by Primary Care Trusts ceased. This study aims to verify this situation and to assess the cost effectiveness of reintroducing vitamin D supplementation in the Burnley Health Care NHS Trust. Methods: Vitamin D deficient patients presenting between January 1994 and May 2005 were identified and data retrospectively collected from their case notes. The cost of treatment and the theoretical cost of primary prevention for the Trust population were calculated using previous and current DoH guidelines. Results: Fourteen patients were identified, of whom 86% presented in the last 5 years and 93% were of Asian origin. The incidence of vitamin D deficiency for our population is 1 in 923 children overall and 1 in 117 in children of Asian origin. The average cost of treatment for each such child is £2500, while the theoretical cost of prevention of vitamin D deficiency in the Asian population through primary prevention according to COMA guidance is £2400 per case. Conclusions: Vitamin D deficiency is re-emerging in our Trust. The overwhelming majority of our patients are of Asian origin. The cost of primary prevention for this high risk population compares favourably both medically and financially with treatment of established disease. We suggest that Primary Care Trusts provide funds for vitamin D supplementation of Asian children for at least the first 2 years of life.</abstract><cop>London</cop><pub>BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health</pub><pmid>16945992</pmid><doi>10.1136/adc.2006.098467</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record>
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subjects 25-hydroxycholecalciferol
25OHC
Age
alkaline phosphatase
ALP
Babies
Biological and medical sciences
Care and treatment
Catchment areas
Child, Preschool
Coding
COMA
Committee on Medical Aspects of Food and Nutritional Policy
cost-benefit
Cystic fibrosis
Demographics
Department of Health
Departments
Dietary supplements
DoH
Drug Costs
Female
Humans
hypocalcaemia
Infant
Infant, Newborn
Male
Medical sciences
Metabolic diseases
Miscellaneous
Original
Patients
Pediatrics
Population
Pregnancy
Prevention
Prevention and actions
Public health. Hygiene
Public health. Hygiene-occupational medicine
Radiation
reference nutrient intake
Retrospective Studies
Rickets
RNI
treatment
Trust departments
Vitamin D
Vitamin D - economics
Vitamin D - therapeutic use
Vitamin D deficiency
Vitamin D Deficiency - drug therapy
Vitamin D Deficiency - economics
Vitamin D Deficiency - prevention & control
vitamin D supplementation
Vitamin deficiency
Young Children
title Vitamin D deficiency: prevention or treatment?
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