Variability of nm23-H1/NDPK-A expression in human lymphomas and its relation to tumour aggressiveness

The nm23-H1 gene is a putative metastasis-suppressor gene encoding a 17 kDa protein with nucleoside diphosphate kinase activity. Expression of nm23-H1/NDPK-A correlates inversely with the metastasising potential of some human tumours and experimental animal cells. No nm23 expression studies exist fo...

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Veröffentlicht in:	British journal of cancer 1996-12, Vol.74 (11), p.1693-1698
Hauptverfasser:	Aryee, DNT, Simonitsch, I, Mosberger, I, Kos, K, Mann, G, Schlögl, E, Pötschger, U, Gadner, H, Radaszkiewicz, T, Kovar, H
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Aged, 80 and over Antibodies, Neoplasm - immunology Biological and medical sciences Biomedical and Life Sciences Biomedicine Cancer Research Child Child, Preschool DNA Mutational Analysis Drug Resistance Epidemiology experimental-oncology Female Genes, Tumor Suppressor Hematologic and hematopoietic diseases Hodgkin Disease - genetics Hodgkin Disease - immunology Hodgkin Disease - metabolism Hodgkin Disease - pathology Humans Infant Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Lymphoma, Non-Hodgkin - genetics Lymphoma, Non-Hodgkin - immunology Lymphoma, Non-Hodgkin - metabolism Lymphoma, Non-Hodgkin - pathology Male Medical sciences Middle Aged Molecular Medicine Monomeric GTP-Binding Proteins Neoplasm Proteins - genetics Neoplasm Proteins - metabolism NM23 Nucleoside Diphosphate Kinases Nucleoside-Diphosphate Kinase Oncology Polymerase Chain Reaction - methods RNA, Messenger - genetics RNA, Messenger - metabolism Transcription Factors - genetics Transcription Factors - metabolism
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