The relationship between weight loss and interleukin 6 in non-small-cell lung cancer

The relationship between weight loss and interleukin 6 in non-small-cell lung cancer

Markers of the inflammatory response, interleukin 6, C-reactive protein, albumin and full blood count, were measured in non-small-cell lung cancer (NSCLC) patients (n = 21) with and without weight loss ( > 5%). There were significant increases in circulating C-reactive protein (P < 0.001), int...

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Veröffentlicht in:British journal of cancer 1996-06, Vol.73 (12), p.1560-1562
Hauptverfasser: SCOTT, H. R, MCMILLAN, D. C, CRILLY, A, MCARDLE, C. S, MILROY, R
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Sprache:eng
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Acute-Phase Reaction - blood
Aged
Aged, 80 and over
Biological and medical sciences
Carcinoma, Non-Small-Cell Lung - blood
Female
Humans
Interleukin-6 - blood
Lung Neoplasms - blood
Male
Medical sciences
Middle Aged
Pneumology
Tumors of the respiratory system and mediastinum
Weight Loss - physiology
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container_end_page 1562
container_issue 12
container_start_page 1560
container_title British journal of cancer
container_volume 73
creator SCOTT, H. R
MCMILLAN, D. C
CRILLY, A
MCARDLE, C. S
MILROY, R
description Markers of the inflammatory response, interleukin 6, C-reactive protein, albumin and full blood count, were measured in non-small-cell lung cancer (NSCLC) patients (n = 21) with and without weight loss ( > 5%). There were significant increases in circulating C-reactive protein (P < 0.001), interleukin 6 (P < 0.01) and platelets (P < 0.01) in the weight-losing group. Moreover, there was a statistically significant correlation (r = 0.785, P < 0.001) between interleukin 6 and C-reactive protein concentrations. These results are consistent with interleukin 6 and the acute phase response promoting weight loss in NSCLC.
doi_str_mv 10.1038/bjc.1996.294
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S</au><au>MILROY, R</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The relationship between weight loss and interleukin 6 in non-small-cell lung cancer</atitle><jtitle>British journal of cancer</jtitle><addtitle>Br J Cancer</addtitle><date>1996-06-01</date><risdate>1996</risdate><volume>73</volume><issue>12</issue><spage>1560</spage><epage>1562</epage><pages>1560-1562</pages><issn>0007-0920</issn><eissn>1532-1827</eissn><coden>BJCAAI</coden><abstract>Markers of the inflammatory response, interleukin 6, C-reactive protein, albumin and full blood count, were measured in non-small-cell lung cancer (NSCLC) patients (n = 21) with and without weight loss ( &gt; 5%). There were significant increases in circulating C-reactive protein (P &lt; 0.001), interleukin 6 (P &lt; 0.01) and platelets (P &lt; 0.01) in the weight-losing group. 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subjects Acute-Phase Reaction - blood
Aged
Aged, 80 and over
Biological and medical sciences
Carcinoma, Non-Small-Cell Lung - blood
Female
Humans
Interleukin-6 - blood
Lung Neoplasms - blood
Male
Medical sciences
Middle Aged
Pneumology
Tumors of the respiratory system and mediastinum
Weight Loss - physiology
title The relationship between weight loss and interleukin 6 in non-small-cell lung cancer
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