Fine mapping of multiple interacting quantitative trait loci using combined linkage disequilibrium and linkage information

Quantitative trait loci （QTL） and their additive, dominance and epistatic effects play a critical role in complex trait variation. It is often infeasible to detect multiple interacting QTL due to main effects often being confounded by interaction effects. Positioning interacting QTL within a small r...

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Veröffentlicht in:	Journal of Zhejiang University. B. Science 2007-11, Vol.8 (11), p.787-791
Hauptverfasser:	Lee, Sang Hong, van der Werf, J H Julius
Format:	Artikel
Sprache:	eng
Schlagworte:	Chromosome Mapping Epistasis, Genetic Gene loci Genetic Linkage Genetics Genomics Genotype & phenotype Humans LDL Linkage Disequilibrium Monte Carlo Method Quantitative Genetics Quantitative Trait Loci - genetics 上位效应数量性状遗传学
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