Function and dynamics of PKD2 in Chlamydomonas reinhardtii flagella

To analyze the function of ciliary polycystic kidney disease 2 (PKD2) and its relationship to intraflagellar transport (IFT), we cloned the gene encoding Chlamydomonas reinhardtii PKD2 (CrPKD2), a protein with the characteristics of PKD2 family members. Three forms of this protein (210, 120, and 90...

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Veröffentlicht in:	The Journal of cell biology 2007-11, Vol.179 (3), p.501-514
Hauptverfasser:	Huang, Kaiyao, Diener, Dennis R, Mitchell, Aaron, Pazour, Gregory J, Witman, George B, Rosenbaum, Joel L
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Antibodies Biological Transport Cell Adhesion Cells Cellular biology Chlamydomonas reinhardtii Chlamydomonas reinhardtii - metabolism Cilia Cloning, Molecular Complementary DNA Flagella Flagella - metabolism Fluorescence Gametes Genes Green Fluorescent Proteins - metabolism Kidney diseases Models, Biological Molecular Sequence Data Nephrology Nucleic Acid Hybridization P branes Polycystic kidney diseases Protein Structure, Tertiary Proteins Ribonucleic acid RNA RNA Interference Temperature TRPP Cation Channels - chemistry TRPP Cation Channels - metabolism
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