Neural crest-derived cells with stem cell features can be traced back to multiple lineages in the adult skin

Given their accessibility, multipotent skin-derived cells might be useful for future cell replacement therapies. We describe the isolation of multipotent stem cell-like cells from the adult trunk skin of mice and humans that express the neural crest stem cell markers p75 and Sox10 and display extens...

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Veröffentlicht in:	The Journal of cell biology 2006-12, Vol.175 (6), p.1005-1015
Hauptverfasser:	Wong, Christine E, Paratore, Christian, Dours-Zimmermann, María T, Rochat, Ariane, Pietri, Thomas, Suter, Ueli, Zimmermann, Dieter R, Dufour, Sylvie, Thiery, Jean Paul, Meijer, Dies, Beermann, Friedrich, Barrandon, Yann, Sommer, Lukas
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipocytes - cytology Adipocytes - metabolism Adult Adult stem cells Animals Cell Differentiation Cell Lineage Cells, Cultured Cellular biology DNA-Binding Proteins - metabolism Face Female Fluorescent Antibody Technique Genomics Hair Follicle - cytology Hair Follicle - physiology High Mobility Group Proteins - metabolism Humans Male Mapping Melanocytes Melanocytes - cytology Melanocytes - physiology Mesenchymal stem cells Mice Mice, Inbred C57BL Middle Aged Multipotent stem cells Multipotent Stem Cells - cytology Multipotent Stem Cells - physiology Neural crest Neural Crest - cytology Neural Crest - physiology Neural stem cells Neuroglia - cytology Neuroglia - physiology Neurons Skin Skin - cytology SOXE Transcription Factors Stem cells Transcription Factors - metabolism
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