Immunogenetic risk and protective factors for juvenile dermatomyositis in Caucasians

Objective To define the relative importance (RI) of class II major histocompatibility complex (MHC) alleles and peptide binding motifs as risk or protective factors for juvenile dermatomyositis (DM), and to compare these with HLA associations in adult DM. Methods DRB1 and DQA1 typing was performed i...

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Veröffentlicht in:	Arthritis and rheumatism 2006-12, Vol.54 (12), p.3979-3987
Hauptverfasser:	Mamyrova, Gulnara, O'Hanlon, Terrance P., Monroe, Jason B., Carrick, Danielle Mercatante, Malley, James D., Adams, Sharon, Reed, Ann M., Shamim, Ejaz A., James‐Newton, Laura, Miller, Frederick W., Rider, Lisa G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Binding Sites Biological and medical sciences Dermatomyositis - diagnosis Dermatomyositis - genetics Dermatomyositis - immunology European Continental Ancestry Group - genetics Genetic Predisposition to Disease Histocompatibility Testing HLA-DQ alpha-Chains HLA-DQ Antigens - genetics HLA-DQ Antigens - immunology HLA-DR Antigens - genetics HLA-DR Antigens - immunology HLA-DRB1 Chains Humans Medical sciences Odds Ratio Risk Factors Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis
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